Desmodium pulchellum

Namn: synonym till Phyllodium pulchellum

Innehåller: DMT, 5-MeO-DMT, Bufotenin, betakarboliner m.m.

Generell information

Desmodium pulchellum är en 0.5 - 1.5m hög buske som tillhört släktet Desmodium (numera Phyllodium) i familjen Fabaceae. Den återfinns naturligt i större delen av Södra Asien och Oceanien (Australien m.fl).

Utöver innehållet av psykoaktiva tryptaminer innehåller den även substanser med medicinska egenskaper, bland användningsområdena kan nämnas avmaskningsmedel, motverkar fibroser i levern, har antiinflammatoriska och antidiabetiska egenskaper, m.m.[1]. Därtill finns en rad användningsområden (exempelvis mot njursten, reumatism, ögonbesvär) i folkmedicinen som inte har undersökts närmare av forskare ännu.

Om innehållet

D. pulchellum whole plant from India has yielded 0.3% alkaloids in one test [including, as % of plant, 0.2-0.25% 5-MeO-DMT, and 0.0018% of combined DMT, DMT N-oxide and bufotenine] (Ghosal & Mukherjee 1964); another test also found 0.0004% 5-MeO-DMT N-oxide, 5-MeO-NMT and gramine (Ghosal & Mukherjee 1966[2]). The root of the young seedling has yielded c. 0.27% DMT, 0.011% DMT N-oxide, 0.041% DMT N-methylcation, 0.022% N-methyl-serotonin, traces of 5-MeO-NMT, 0.026% adrenoglomerulotropin and traces of 6-MeO-N-methyl-b-carbolinium salt; root of mature plants yielded 0.067-0.451% DMT, 0.012-0.121% DMT N-oxide, 0.022-0.132% 5-MeO-DMT, 0.013% N-methyl-serotonin, 0.0015% 3-alkylindole, 0.001% 5-OH-3-alkylindole, and traces of bufotenine, bufotenine N-oxide and 2-methyl-pinoline. Stem and leaf of mature plants yielded 0.294% DMT, 0.07% DMT N-oxide, 0.476% 5-MeO-DMT, 0.154% 5-MeO-tryptamine, 0.112% bufotenine and traces of bufotenine N-oxide. Green fruits and ripe seeds yielded 0.001% DMT, up to 0.007% DMT N-oxide and c.0.002% each of 5-MeO-DMT and 5-MeO-tryptamine; harman, tetrahydroharman and pinoline were also found in seeds, harman also in fruits (Ghosal 1972; Ghosal et al. 1972c[3]). The plant has also yielded hordenine, norharman, 2-methyl-THbC, 2-methyl-b-carbolinium quaternary salt, 1,2-dimethyl-6-MeO-THbC, melinonine F, and canavanine. In dogs, the stem-leaf alkaloids [0.1mg/kg i.v.] caused initial respiratory stimulation, followed by hypotension and severe bronchoconstriction, which resulted in death in some cases; cardiac depression was also observed. Alkaloids of the green fruits and seeds inhibited cholinesterase (Bell et al. 1978; Ghosal 1972; Ghosal & Mukherjee 1966; Ghosal et al. 1970b, 1972c; Harborne et al. ed. 1971; Shulgin & Shulgin 1997).
— Garden of Eden

Externa länkar

  1. Phyllodium Pulchellum: A Potential Medicinal Plant - A Review (Velmurugan et al. 2014)
  2. Indole-3-alkylamine Bases of Desmodium pulchellum (Ghosal & Mukherjee, 1966) se även pdf-version
  3. Chemical And Pharmacological Evaluation Of Desmodium Pulchellum (Ghosal et al. 1972)

Trout’s Notes on the Genus Desmodium (1997), s.16

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